Human Research

Human subject laboratory: This includes two 200 sq. ft. rooms and ancillary meeting rooms. The instrumentation provides capabilities for evaluating sensorimotor integration and conducting brain mapping and cognitive behavior assessment. Description of the research instrumentation and capabilities is given below.


Motion Capture System (PhaseSpace) Motion Capture System (PhaseSpace)

This system is used to capture high-speed (up to 480Hz) human motion through active infra-red markers. This system can perform accurate, real-time tracking of multiple markers, continuous auto-identification of each marker while in view of the cameras, and instant identification when a marker reappears after occlusion. We can use this system for tracking and analysis of movement of limb joints in human subjects.






Wireless EMG system (DELSYS Trigno)

Wireless EMG system (DELSYS Trigno)

This system has wireless portable hybrid EMG/accelerometer sensors to measure electromyography as well as movement from up to 16 channels. This system delivers high-quality performance with motion artifact suppression and provides 8-hr continuous wireless recordings.

Mobility Lab™ (APDM)Mobility Lab™ (APDM)

This system is a gait analysis system that uses inertial measurement units. Mobility lab™ is a portable unit that can provide multitude of gait and balance parameters. The system makes it easy to collect, analyze, and store gait outcome measures. After data is collected using intuitive software, a report is automatically generated to compare subject's data against normative values.





Tucker-Davis Technologies BioAMP Processor and StimulatorTucker-Davis Technologies BioAMP Processor and Stimulator

The RZ2 BioAmp Processor has been designed for high channel count real-time neurophysiological recording and signal processing. Combined with the real-time processing capabilities of the RZ Processors, the IZ2 Stimulator enables dynamic closed-loop stimulation paradigms.





Bertec Force Plates (4060-07)

Bertec's 4060-07 force plates are used for clinical and research gait analysis. Force plates contain strain gaged load transducers that precisely measure six components (6-DOF): three orthogonal forces and the moments about each axis. The AM6504 analog amplifier, with 4 selectable gain settings, can be used with the force plates for different applications such as measuring braking, loading and propulsion forces (ground reaction forces) during a running gait trial or computing the center-of-pressure location in a balance trial.






Electroencephalography (ANT-Neuro)Electroencephalography (ANT-Neuro)

The ASA-Lab EEG recording system from ANT-Neuro reads minute surface voltage from the scalp and provides excellent quality signals. Active shielding allows patients to move during recordings without compromising data quality. The system can also record EMG (muscles), EOG (eyes), heart (EKG), temperature, GSR (sweat), and signals from a respiration belt (breathing) and/or acceleration sensors. An additional advantage of the active shielding is that TMS can be used simultaneously on the brain during continuous EEG recordings (normally these two techniques interfere with one another). The Visor TMS neuro-navigation system can be used to determine the 3-dimensional location of stimulation within the brain and the Neuro BCI software developmental kit can be used to customize the system to conduct real-time neurofeedback research.


Functional Near-Infrared Spectroscopy (NIRScout)Functional Near-Infrared Spectroscopy (NIRScout)

The NIRScout is a-compact non-invasive neuroimaging solution that measures real-time brain activity hemodynamic responses from up to 384 channels per frame. It can interface seamlessly with several EEG, MRI, TMS, and Eyetracking systems. This system has several digital input/output options for precise event marker triggering. Real-time data streaming is available for brain-computer-interface and neurofeedback research. The NIRScout employs an open data format that is compatible with a variety of open-source analysis solutions as well as NIRx's proprietary nirsLAB and NAVI analysis software environments. NAVI software generates multifunctional 2D/3D volume rendering and 2D/3D FEM mesh generation.


Transcranial Magnetic Stimulation (MagPro R30)Transcranial Magnetic Stimulation (MagPro R30)

The MagPro R30 from MagVenture can be used for a number of applications, including the examination of the physiology of the motor pathways in the central and peripheral nervous systems and TMS and repetitive TMS research. This system can deliver monophasic or biphasic waveforms at rates up to 30 pulses per second (pps), and can deliver dual pulses with up to 5 pulse pairs per second. In addition, this system is operated and controlled via a built-in computer, can store up to 27 different protocols, and can be connected to an EMG system. The coil is a model C-B60 Butterfly coil which is used for focused stimulations and can deliver 350 pulses at 1pps before warming up to room temperature.


Systems integration

The ASA-Lab software along with the VISOR navigation system has the capability to integrate and synchronize TMS, fNIRS and EEG in one session. This integration of systems enables us to measure brain activity with good spatial and temporal resolution. We can also combine these capabilities with PhaseSpace for tracking body joint movements and force plates. All of these systems can be used simultaneously so that subjects can undergo transcranial magnetic stimulation and electroencephalogram testing or have motion monitored at the same time.